Pulmonary and Respiratory Trauma in Infants and Children: A State-of-the-Art Review of Mechanisms, Diagnosis, Contemporary Management, and Outcomes
DOI:
https://doi.org/10.68050/JAMS.2026.742Keywords:
Congenital lung malformations; CPAM; bronchopulmonary sequestration; congenital lobar overinflation; congenital diaphragmatic hernia; congenital airway anomalies; paediatric thoracic surgery; bronchoscopy.Abstract
Background
Pulmonary and respiratory trauma remains a major cause of morbidity and mortality in infants and children worldwide. Although blunt thoracic trauma accounts for most injuries, important causes include birth-related trauma, ventilator-associated barotrauma, child abuse, penetrating injuries, blast injuries, aviation disasters, and iatrogenic complications. Unique anatomical and physiological characteristics of children result in injury patterns that differ substantially from those observed in adults.
Objective
To review the epidemiology, mechanisms, pathophysiology, diagnosis, imaging, contemporary management, and long-term outcomes of pulmonary and respiratory trauma in infants and children.
Data Sources
A narrative review of contemporary literature indexed in PubMed, Scopus, Embase, and major pediatric trauma, respiratory, and critical care journals published between 2020 and 2026.
Results
Pulmonary contusion remains the most common pediatric thoracic injury and frequently occurs in the absence of rib fractures owing to increased chest wall compliance. Advances in trauma imaging, point-of-care ultrasonography, low-dose computed tomography, bronchoscopy, thoracoscopy, and extracorporeal membrane oxygenation have significantly improved diagnostic accuracy and clinical outcomes. Ventilator-induced lung injury, child abuse-related thoracic trauma, blast injury, and iatrogenic respiratory trauma continue to present major management challenges. Contemporary care increasingly emphasizes multidisciplinary management, lung-protective ventilation, minimally invasive intervention, and individualized treatment strategies.
Conclusions
Early recognition, appropriate imaging, and multidisciplinary management are critical for optimizing outcomes following pediatric pulmonary trauma. Emerging technologies including artificial intelligence-assisted imaging, advanced ventilatory monitoring, and international pediatric trauma registries are expected to further improve diagnosis and evidence-based care.
References
1. Sweet AAR, de Bruin IGJ, Peek J, IJpma FFA, van Baal MCPM, Leenen LPH, Houwert RMH. Epidemiology and outcomes of traumatic chest injuries in children: a nationwide study in the Netherlands. Eur J Pediatr. 2023;182(4):1887-1896. doi:10.1007/s00431-023-04828-1. PMID:36807757.
2. Özdülger A. Thoracic trauma in children. Turk Gogus Kalp Damar Cerrahisi Derg. 2024;32(Suppl 1):S21-S28.
3. Eisenberg M, Bachur RG, Wiley JF. Thoracic trauma in children: initial stabilization and evaluation. Updated 2024.
4. Royal College of Radiologists. Major paediatric trauma radiology guidance. London: RCR; 2024.
5. Angurana SK, Sudeep KC, Prasad S. Ventilator-induced lung injury in children. J Pediatr Crit Care. 2023. doi:10.4103/jpcc.jpcc_27_23.
6. Li LC, Yang DH, Yang M, Zhang H, Li L, Lu XY, Wang L, Luo H. Ventilator-induced lung injury: from mechanisms to integrated clinical management. Front Med. 2026;12:1789457.
doi:10.3389/fmed.2026.1789457. PMID:41868223.
7. Costa A, Sakho B, Gomez S, Khanyan B, Leybengrub P, Bergese S. Ventilator-induced lung injury: pathophysiology, prevention, and emerging therapeutic strategies. Int J Mol Sci. 2025;26(21):10448. doi:10.3390/ijms262110448.
8. Aly H, Massaro AN, Patel K, El-Mohandes AAE. Is it safer to intubate premature infants in the delivery room? Pediatrics. 2005;115(6):1660-1665. doi:10.1542/peds.2004-1534. PMID:15930234.
9. Sweet DG, Carnielli V, Greisen G, Hallman M, Ozek E, Plavka R, et al. European Consensus Guidelines on the Management of Respiratory Distress Syndrome: 2023 Update. Neonatology. 2023;120(1):3-23. doi:10.1159/000528914. PMID:36863329.
10. Jeng MJ, Lee YS, Tsao PC, Soong WJ. Neonatal air leak syndrome and the role of mechanical ventilation. Pediatr Neonatol. 2012;53(6):368-374. doi:10.1016/j.pedneo.2012.10.001. PMID:23290955.
11. Moore HB, Moore EE, Burlew CC, et al. Trauma thoracotomy and management of penetrating thoracic trauma in children. J Trauma Acute Care Surg. 2022; 92(4):755-763.
12. Korkmaz I, Celikkaya ME. Blast lung injury in children: injury patterns and associated organ injuries. Pediatr Emerg Care. 2023;39(9):715-720. doi:10.1097/PEC.0000000000003021. PMID:37463251.
13. Ortega R, Vietor R, Arbelaez C, Feliu D, Nozari A, Ortoleva J. Blast injuries. N Engl J Med. 2024; 391(16):e31. doi:10.1056/NEJMvcm2408353.
14. Kuo W, Goodkin HP, Cohen RA, et al. Artificial intelligence applications in pediatric emergency and trauma imaging. Radiographics. 2024; 44(3):e230117.
15. Topjian AA, Raymond TT, Atkins D, et al. Pediatric trauma registries and future directions in outcome research. Pediatr Crit Care Med. 2024;25(2):e101-e110.
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